Endocrine Abstracts

Background: Parathyroid hormone (PTH) is a peptide hormone consisting of 84 amino acids with residues 1–34 responsible for its biological activity. Hypoparathyroidism is a rare, complex condition with a patient predisposition toward impaired mineral homeostasis. Replacement with Natpara (PTH 1-84) requires daily injections and is still complicated by fluctuating calcium levels. An unmet need exists for a long-acting treatment that is effective. It is hypothesised that a P...